Wait, so does she want to open a business or does she want to go into realty? If she's looking to go into realty, I found an interesting article on licensing, but if she's considering opening a business which leaves her susceptible to liability, I would definitely consider reading up on protecting your small business. Either way, it's running your own business is definitely a huge responsibilty, but for some it is overwhelmingly rewarding, I wish you both the best of luck, her especially!